Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000770654 ACRIDINE-9-CARBOXALD 1G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000772747 ACRIDINE-9-CARBOXALD 100MG
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Medchemexpress LLC Heptadecan-9-amine | 3241-20-1 | MFCD30742905 | >96.0% | 255.48 g/mol | C17H37N | 5 G
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Heptadecan-9-amine is a long-chain primary aliphatic amine used as a chemical building block and research reagent in organic synthesis and biochemical applications. Supplied in laboratory-scale quantities, it should be stored refrigerated and protected from light to preserve stability.
- Primary aliphatic C17 amine.
- Molecular formula: C17H37N.
- Molecular weight: 255.48 g/mol.
- CAS number: 3241-20-1.
- Appearance: colorless to light yellow liquid.
- Storage: 4°C, protect from light.
- Available in laboratory pack sizes, including 5 G.
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Medchemexpress LLC Amine-PEG-CH2COOH | 95.0% | 100 MG
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Amine-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins by facilitating the connection between an E3 ubiquitin ligase and the target protein.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Appears as a solid with a light yellow to yellow color
- For research use only
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
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Medchemexpress LLC Quin-C7 | 871100-12-8 | MFCD34182190 | 99.8% | 431.48 g/mol | C25H25N3O4 | 10 MG
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Quin-C7 is an orally active antagonist of formyl peptide receptor 2 (FPR2/ALX) used as a research reagent to study inflammatory signaling pathways. It exhibits anti-inflammatory activity and has been reported to ameliorate dextran sulfate sodium (DSS)-induced colitis in mouse models.
- Orally active FPR2/ALX antagonist for in vivo and in vitro studies.
- Demonstrated anti-inflammatory effects and efficacy in DSS-induced colitis models.
- Chemical formula C25H25N3O4, molecular weight 431.48 g/mol.
- CAS number 871100-12-8.
- High purity (~99.8%) suitable for research applications.
- Available as a 10 MG solid; soluble in DMSO for stock solutions.
- For research use only; not for human or clinical use.
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Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.17 | 100 G
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2-Aminoquinoline is a promising compound as a bioavailable nNOS inhibitor, despite exhibiting low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. It demonstrates antiviral activity against the vaccinia virus and has potential for research into antineurodegenerative agents. This product is for research use only.
- Antiviral activity against vaccinia virus.
- Potential for research into antineurodegenerative agents.
- For research use only.
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Medchemexpress LLC 3,6-Acridinediamine, N3,N3,N6,N6-tetramethyl- | 494-38-2 | 96.58% | 500 MG
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Acridine Orange base is a cell-permeable fluorescent dye. It stains various organisms such as bacteria, parasites, and viruses bright orange. When used under appropriate conditions (pH=3.5, Ex=460 nm), it can distinguish human cells in green for detection by fluorescence microscopy. This dye fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644). It can also be utilized in cell cycle assays.
- Cell-permeable fluorescent dye.
- Stains organisms bright orange.
- Distinguishes human cells in green under specific conditions.
- Fluoresces green when bound to dsDNA.
- Fluoresces red when bound to ssDNA or ssRNA.
- Can be used in cell cycle assays.
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Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.
- Selective PROTAC PTPN2 degrader
- Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
- Promotes T cell activation
- Amplifies IFN-γ-mediated anticancer activity
- Composed of a PTPN2 ligand, a linker, and a VHL ligand
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Medchemexpress LLC LM11A-31 100mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 100 MG
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LM11A-31 a non-peptide p75NTR (neurotrophin receptor p75) modulator is an orally active and potent proNGF (nerve growth factor) antagonist LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer s disease mouse models with mid- to late-stage disease progression[1][2]
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Medchemexpress LLC hsa-miR-31-5p mimic 5nmol | 5nmol
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hsa-miR-31-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
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![Medchemexpress LLC 4-[2-(4-nitro-1H-imidazol-1-yl)ethyl]morpholine | 6497-78-5 | MFCD02029312 | >98.0% | 226.24 | C9H14N4O3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242804.png-250.jpg)
Medchemexpress LLC 4-[2-(4-nitro-1H-imidazol-1-yl)ethyl]morpholine | 6497-78-5 | MFCD02029312 | >98.0% | 226.24 | C9H14N4O3 | 5 MG
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RGW-611 (4-[2-(4-nitro-1H-imidazol-1-yl)ethyl]morpholine) is a morpholine derivative used in laboratory research; it has been reported to enhance radiation-induced cell death in hypoxic cell models and to stimulate fatty acid synthesis. The compound is supplied in small quantities for in vitro studies and requires controlled storage to maintain stability.
- Chemical name: 4-[2-(4-nitro-1H-imidazol-1-yl)ethyl]morpholine.
- CAS number: 6497-78-5.
- Molecular formula: C9H14N4O3.
- Molecular weight: 226.24 g/mol.
- Purity: >98.0% (HPLC).
- Available sizes: 1 mg, 5 mg, 10 mg.
- Storage: 4°C, protect from light; in solvent store at -80°C for long-term.
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Selleck Chemical LLC Cilostazol 100mg 73963-72-1 OPC-13013
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Cilostazol (OPC-13013) is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 ?M and inhibitor of adenosine uptake. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Medchemexpress LLC hsa-miR-31-5p mimic 20nmol | 20nmol
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hsa-miR-31-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
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Medchemexpress LLC 4-((3-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carbonyl)oxy | 1092369-24-8 | MFCD31631580 | 99.6% | 624.72 g·mol⁻¹ | C34H44N2O9 | 50 MG
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SLF-amido-C2-COOH is a synthetic FKBP12-binding ligand used as a PROTAC building block. It couples an SLF recognition motif to a short linker ending in a carboxylic acid, providing a convenient functional handle for conjugation in bifunctional degrader synthesis.
- Acts as an FKBP12-binding moiety for PROTAC construction.
- Provides a carboxylic acid handle for amide or ester coupling.
- Compatible with standard small-molecule coupling chemistries.
- High purity suitable for research applications (≈99.6%).
- Molecular formula C34H44N2O9; molecular weight 624.72 g·mol⁻¹.
- Supplied as an off-white to white solid for synthetic use.
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=O | 250mg | 517090861](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000129387.jpg-250.jpg)
eMolecules 79025-28-8 | 3,4-Dimethoxy-2-nitrobenzoic acid | Combi-Blocks | MFCD00074884 | 227.172 | C9H9NO6 | 95.000 | COc1ccc(C(O)=O)c(c1OC)[N+]([O-])=O | 250mg | 517090861
3,4-Dimethoxy-2-nitrobenzoic acid | Combi-Blocks | 79025-28-8 | MFCD00074884 | 227.172 | C9H9NO6 | 95.000 | COc1ccc(C(O)=O)c(c1OC)[N+]([O-])=O | 250mg | 517090861
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